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LOT: BIO-25-20592-D
Emideltide (DSIP)
Emideltide, also known as Delta Sleep-Inducing Peptide (DSIP), is a neuroactive nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, first isolated in 1977 by the Schoenenberger-Monnier group from rabbit cerebral venous blood during slow-wave sleep studies. It interacts with hypothalamic-pituitary pathways and has been investigated in models of sleep architecture regulation, stress-response adaptation, and neuroendocrine hormone balance. Early human studies demonstrated significant increases in delta sleep and improved sleep efficiency following DSIP administration. It has also been explored for fatigue management, withdrawal support, and neuroendocrine modulation, exhibiting a wide range of CNS-related experimental activity.
Research Benefits
- Supports sleep onset and delta-wave sleep architecture in preclinical and early human research models
- Modulates hypothalamic-pituitary stress-response signaling and neuroendocrine hormone patterns
- Investigated for fatigue reduction and recovery support in stress-adaptation research
Size
Quantity
Total Price$51.15
Emideltide (DSIP) is a synthetic nonapeptide composed of nine amino acids with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, and a molecular weight of approximately 849 Da. It was originally isolated from rabbit cerebral venous blood during slow-wave sleep and was initially regarded as a candidate sleep-promoting factor. Since its isolation in 1977, DSIP has been studied in controlled experimental settings for its potential influence on sleep regulation, neuroendocrine hormone secretion, and central nervous system stress-response pathways.